Echocardiography as a noninvasive Swan-Ganz catheter.

نویسنده

  • Jae K Oh
چکیده

Diwan and co-investigators report in this issue of Circulation that the interval between onset of mitral E and annular early diastolic velocity (Ea) by tissue Doppler, TE Ea, can be used to estimate left ventricular (LV) filling pressure in patients with mitral valve disease.1 Garcia and colleagues were the first to report that the onset of Ea occurred 7.5 3.5 ms after peak mitral inflow velocity in 7 patients with restrictive cardiomyopathy, whereas Ea started 22 19 ms earlier than did E in the normal group.2 Subsequently, TE Ea has been shown to correlate with the time constant of LV relaxation ( ) demonstrated by Hasegawa and associates in their elegant animal experiment.3 With worsening of heart failure by rapid pacing, Ea progressively decreased in velocity and delayed in onset. Mitral E occurred coincidently with the termination of the early diastolic left arterial (LA) and LV pressure gradient at baseline and all stages of heart failure. In contrast, with increasing heart failure, Ea was progressively delayed after LA to LV pressure crossover, and TE Ea was related to . Rivas-Gotz, Nagueh, and their associates also demonstrated that TE Ea was prolonged after constriction of the circumflex coronary artery in dogs.4 In patients with heart failure, LV myocardial relaxation and compliance are decreased.

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عنوان ژورنال:
  • Circulation

دوره 111 24  شماره 

صفحات  -

تاریخ انتشار 2005